Development & Application of Real World Evidence (RWE) Based BIG DATA Platforms: Implications for R&D and Clinical Decision Support

This presentation will discuss critical data science aspects involved in developing RWE data platforms, technical & logistical challenges related to RWE, and strategic application of RWE in the R&D space. Specific focus will be given on leveraging RWE to inform Target Product Profiles (TPPs), Trial designs, Clinical Operations, patient centered strategy and R&D decision support. Two Pharma case studies will be presented across Oncology and neuroscience that will demonstrate the practical details around development of “Fit for Purpose” BIG DATA platforms, data outputs and practical application of gained knowledge towards optimizing clinical programs and development strategy.

Usman Iqbal MD. MPH. MBA is a Senior Medical Affairs Leader- Neuroscience at AstraZeneca, and based in Cambridge, MA. Usman has 12+ years of diverse experience spanning clinical medicine, health policy & management, R&D/Med AFF, Health Economics & Outcomes research (HEOR) across academia and biopharmaceutical. His experience spans number of different therapeutic areas including Oncology, as former Head of Sanofi Oncology, Global Evidence & Value Development (GEVD). As part of both R&D and Med Affairs in different roles, Usman has had been responsible for Portfolio Prioritizations, Integrated Medical Affairs Planning, and End-to-End Evidence generation based on Stakeholder engagement (Patient, Provider, Payer), Market insights and Relative Medical Value Assessment Platforms. Prior to working in the industry that also includes Amgen and Boehringer Ingelheim, Usman was based at Boston University Health Outcomes Technology Group as a senior research fellow and served as a research consultant for Veterans Affairs Pharmacy Benefit Management (VA-PBM), the Centers for Medicare &, Medicaid Services (CMS), the Agency for Healthcare Research and Quality (AHRQ), and the National Committee for Quality Assurance (NCQA). Usman has authored more than 50 publications, and his research experience encompasses BIG DATA evaluations with a specific focus on comparative effectiveness, disease management, physician profiling, patient centered outcomes & access solutions. He is a certified coach practitioner and provides personalized coaching on performance and personal development to a wide range of industry professionals. Usman received his MD from Allama Iqbal Medical College, Lahore, Pakistan and Master of Public Health and Master of Business Administration from Boston University.